Most toxic plants are only hazardous if actually ingested; touching them (with a few notable exceptions, like Poison Ivy and Giant Hogweed) is generally a non-issue, though it's always a good idea to wear gloves, since you never know when someone will be sensitive to the sap or leaf hairs of certain species. (The hairs on azalea and dogwood leaves, for instance, not uncommonly can make people's skin itch. The sap of some members of the carrot or rue families can be skin irritants, or cause skin damage where sap on the skin is exposed to sunlight.) If you were removing Giant Hogweed, whose sap is known to be medically significant in terms of a health risk (eye contact would be dangerous for that species), would require more protective measures like wearing eye and skin protection, but Eupatorium and other species are not that risky. (The common name of Snakeroot may be used for more than one species. We assume you're referring to the native Eupatorium/Ageratina species.)

Miri

You're welcome!