According to the OSU Extension publication, How to Reduce Bee Poisoning
From Pesticides, neem oil, an insecticide made from a neem tree, does
not have a precautionary statement regarding bees on its label.
Therefore, no bee caution is necessary. The neem must be ingested in
order for it to be toxic to bees. Try not to spray on flowers, and
please be sure to follow instructions on the label.
Neem oil has a minimum of a one year shelf life
unopened. As for the mixed solution, you only want to mix up the amount
necessary for the job at hand and it is recommended to use that batch
within approximately 8 hours of mixing due to the neem oil breaking down once mixed. I suggest a new bottle for most effective outcome.
Neem oil is practically non-toxic to birds, mammals, bees and plants. ... It is important to remember that insects must eat the treated plant to be killed. Therefore, bees and other pollinators are not likely to be harmed.
Timing is critical when applying beneficial nematodes. They should be applied to the soil of infested areas to control the pupal stage (early) of the cucumber beetle. If adult feeding damage is identified, apply kaolin clay to plant foliage. The film left behind disorients insects and prevents feeding.
Beneficial nematodes are perishable and don't have a long shelf life so
might be difficult to find locally. Your best bet is to check with your
local well-stocked garden center. Depending on the time of year, they
may have the nematodes in stock. Otherwise, they can order for you.
A word of caution about using nematodes for managing cucumber beetles: T
here is limited scientific research in this area.
There have been studies done, but typically these are limited to
controlled environments (like testing in a laboratory or a greenhouse
setting, but not out in the field or garden exposed to the natural
environment.)
Take some time to read the packaging: There are many
different types of beneficial nematodes available to purchase and not
all nematodes work against all pests. Some of the types that have been
at least lab tested against cucumber beetle are: Steinernema sp. and
Heterorhabditis sp.
Keep in mind that these beneficial nematodes
only affect the soil-dwelling portion of the cucumber beetles life. The
nematodes won't affect the adults that cause the above ground foliage
damage-only the immature larva in the soil. So timing of application of
the nematodes is important.
And
the last caution: the damaging-causing adult beetles are very mobile.
So just because you are diligent in managing them in your own garden-it
doesn't mean they won't just fly in from neighboring yards!