Rose Leaves Have Holes and White Spots
The larger white spots are where rose slugs were feeding. Rose slugs are the larvae of an insect called sawflies. (They are not the slimy slugs that like wet conditions.)
Here's information about how to handle them: https://extension.umd.edu/hgic/topics/rose-slugs-shrubs
If you can find them, you might want to spray spinosad, but it is very probable that you won't find any because they are already through feeding and have left. Don't spray unless you see them.
This feeding does not make a dent in the health of the shrubs, so it is not necessary to do any treatment.