Foundation shrubs have some kind of issue!
It looks like your cherry laurels are showing symptoms of cherry shot hole disease and some old chewing damage by insects.
Cherry shot hole is a foliar fungal disease favored by wet weather. The infected leaf tissue falls out and "shot holes" are left behind. The damage is cosmetic and no chemical controls are recommended.
We cannot identify the white substance on the leaves. The photos are out of focus. You can send us more photos in focus of the white stuff so we can see what you are dealing with.
At this point, we recommend that you lightly prune back any dead branches. Let the plant recover and put out new growth. Monitor the plants this growing season. Make sure mulch is no thicker than several inches and away from the base of the stems. Water during dry periods.
Here is our blog post for more information (possible disease and insect issues) and how to grow cherry laurel in your landscape.