It is really hard to identify the problem from your photos. It could be a number of problems. Here is a link to an article that may help you identify if it is a canker, needlecast or other problems. http://msue.anr.msu.edu/news/what_is_spruce_decline_and_what_should_you_do_about_it
The third picture I am wondering about possibly spruce gall midge. http://msue.anr.msu.edu/news/spruce_gall_midge
I would recommend sending a sample to MSU Diagnostic Services - www.pestid.msu.edu for identification. There may be a fee.