There are only 2 spiders in the US that are venomous to humans, the brown recluse and the black widow. Other spiders may cause some discomfort with a bite depending on an individuals sensitivity (allergic reaction) to the bite. All the spiders have some venom, but most are only effective on insects.
This spider looks like one of the orb spiders, whose bite might be painful but not a health hazard. Bites from these spiders are vary rare. This spider is probably Araneus nordmanni, but could be Araneus saevus or Araneus marmoreus. Colors can vary on all of them.